Shanghai Gamma Knife Hospital

Shanghai Gamma Knife Hospital: An International Benchmark in Precision Radiotherapy

I. Hospital Overview

Shanghai Gamma Knife Hospital is a tertiary specialized hospital approved by the National Health Commission of China. Focusing on stereotactic body radiation therapy (SBRT/SRS) and precision cancer diagnosis and treatment, it ranks among China's earliest specialized hospitals to introduce and clinically apply world-leading Gamma Knife technology. Leveraging the expertise and technical support of the Shanghai Jiao Tong University Affiliated Medical Group, the hospital collaborates with international academic organizations such as the European Society for Radiotherapy and Oncology (ESTRO) and the American Society for Radiation Oncology (ASTRO). It is committed to establishing a precision radiotherapy center that is “domestically leading and internationally renowned.”

Located in the core area of Zhangjiang Science City, Pudong New District, Shanghai, adjacent to the Shanghai International Medical Park, the hospital occupies approximately 30,000 square meters. It offers over 200 beds and treats more than 30,000 patients annually, with over 30% being complex and critical cases from both domestic and international sources. Guided by the core principles of precision, minimally invasive procedures, and high efficiency, the hospital has established a fully digitalized diagnostic and treatment system spanning imaging diagnosis, target delineation, radiotherapy planning, and efficacy assessment. This positions it as a vital hub for precision oncology treatment in East China.

II. Technical Advantages: World-Leading Gamma Knife Technology and Precision Radiotherapy System

Shanghai Gamma Knife Hospital's core competitiveness lies in clinical innovation and the equipment iteration of Gamma Knife technology. The hospital is equipped with the internationally advanced Leksell Gamma Knife Icon® 5th Generation for head tumors and the Perfexion™ Gamma Knife for body tumors. Combined with AI-assisted target planning systems and image-guided radiation therapy (IGRT), treatment accuracy is maintained within 0.1 millimeters, achieving true “millimeter-level precision.”

• Gamma Knife for the Head: Targets intracranial lesions such as gliomas, meningiomas, pituitary tumors, acoustic neuromas, and trigeminal neuralgia. Delivers high-dose irradiation without craniotomy, preserving normal brain tissue function. Achieves a 5-year local control rate exceeding 92% (Source: Clinical Study, Chinese Journal of Radiation Oncology, 2024).

• Body Gamma Knife: Covers solid tumors, including lung cancer, liver cancer, pancreatic cancer, and prostate cancer. Particularly for inoperable early-stage lung cancer (Stages I-II), it achieves a 5-year survival rate of 78%, comparable to traditional surgery. For advanced tumors, it increases local control rates by 40% and significantly extends patient survival.

• Multimodal Fusion Technology: Integrates MRI, CT, PET-CT, and other multi-source imaging data with patient genetic testing results to develop personalized “imaging-pathology-molecular” tripartite treatment plans, boosting treatment efficacy by 30% in complex cases.

III. Key Specialties: Comprehensive Lifecycle Management of Oncology and Neurological Disorders

Guided by the development principle of “specialized excellence with robust comprehensive care,” the hospital prioritizes the following key disciplinary clusters:

1. Neurosurgery (Gamma Knife Center):

Specializing in intracranial tumors, cerebral vascular malformations, and functional neurosurgical conditions, the center performs over 5,000 Gamma Knife procedures annually, maintaining the highest surgical volume in East China for five consecutive years. Led by nationally renowned neurosurgeons, the team excels in integrated “surgery + Gamma Knife + immunotherapy” protocols for gliomas, achieving a median survival exceeding 24 months for glioblastoma patients (compared to the international average of 14.6 months).

2. Comprehensive Tumor Treatment Department:

For challenging tumors like lung, liver, and pancreatic cancers, we implement a multidisciplinary team (MDT) approach combining Gamma Knife, chemotherapy, targeted therapy, and immunotherapy. The department boasts China's first certified “Stereotactic Body Radiation Therapy (SBRT) Experts,” achieving a 95% local control rate for patients with oligometastases (≤5 lesions) and doubling the 5-year survival rate compared to conventional radiotherapy.

3. Radiation Oncology Department:

Equipped with Varian TrueBeam linear accelerators and Elekta Infinity volumetric modulated arc therapy (VMAT) systems, the department delivers a full spectrum of radiotherapy techniques, including conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT), and VMAT. It achieves a 98% radiation damage control rate for head and neck tumors and esophageal cancer.

4. Functional Neurosurgery:

For conditions including Parkinson's disease, essential tremor, and drug-resistant epilepsy, the department performs combined deep-brain stimulation (DBS) and gamma-knife therapy. Postoperative symptom improvement rates reach 85%, with related clinical research supported by the National Natural Science Foundation of China Key Project.

IV. Core Departments and Collaborative System

The hospital has established a comprehensive “diagnosis-treatment-rehabilitation” service chain. In addition to the above specialties, it also features:

• Diagnostic Imaging Department: Equipped with 3.0T MRI, 256-slice spiral CT, PET-MR, and other devices to provide precise imaging assessments;

• Pathology Department: Conducts multidisciplinary pathology consultations (MDT) and maintains a remote diagnostic partnership with the Johns Hopkins Hospital Pathology Center;

• Anesthesiology and Perioperative Medicine Department: Delivers personalized anesthesia protocols for elderly and critically ill patients to ensure surgical safety;

• Rehabilitation Medicine Department: Integrates physical therapy, speech therapy, and psychological interventions to address functional recovery needs following radiation therapy.

V. Medical Equipment: World-Class Devices Empowering Precision Diagnosis and Treatment

The hospital's equipment configuration meets international top-tier standards, with core devices including:

• Leksell Gamma Knife Icon® 5th Generation: Supports frameless positioning and real-time image guidance, enabling treatment of lesions in sensitive areas such as the brainstem and optic nerves;

• Perfexion™ Body Gamma Knife: Treats solid tumors throughout the body with single sessions lasting only 15-30 minutes, ensuring high patient comfort;

• Varian TrueBeam Linear Accelerator: Equipped with AGL (Adaptive Geometric Guidance) system for real-time tumor tracking during radiotherapy;

• 3.0T 70cm Large-Bore MRI: Supports whole-body diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) for precise tumor activity assessment;

• PET-CT (Biograph Vision 600): 2mm resolution for early detection of micro-metastases (≤5mm diameter).

VI. International Patient Services: Seamless Global Care Experience

As a Shanghai-designated “International Medical Tourism Pilot Unit,” Shanghai Gamma Knife Hospital offers international patients one-stop, multilingual, customized services:

• Language Support: Professional interpreters fluent in 10 languages, including English, Japanese, Korean, French, and Spanish. Key departments (e.g., Radiation Oncology, Neurosurgery) staff physicians certified by international medical accreditation (ECFMG).

• International Medical Department: Dedicated ward area with international standard nurse-to-patient ratio (1:0.6), offering bilingual nursing, cross-border medical document translation, and direct billing for overseas insurance (covering major providers like U.S. Blue Cross, UK BUPA);

• Convenient Access: Exclusive appointment channels for international patients (official website/WeChat account), airport/station pickup service, and dedicated patient guides assisting with registration, examinations, and medication pickup;

• Telemedicine: Established remote consultation systems with institutions like MD Anderson Cancer Center (USA) and Cancer Institute Hospital (Japan), enabling patients to obtain second opinions from international specialists in real time;

• Follow-up Management: Provides 3 years of complimentary post-treatment follow-up services, tracking treatment efficacy via video consultations and adjusting rehabilitation plans as needed.

VII. International Patient Testimonials: “Dual Recognition of Efficacy and Care”

• John (U.S., lung cancer recurrence after surgery): “The Gamma Knife treatment here is precise to the millimeter. My tumor shrank by 60% in just three months. The medical team explained every step of the treatment in English, giving me complete peace of mind.”

• Japanese Patient Yuki (Meningioma): “My entire hospital stay lasted just five days. Nurses checked on me daily in Japanese, and upon discharge, they provided a comprehensive recovery guide (bilingual Chinese-Japanese). Such thoughtful care!”

• Korean Patient Minho (Liver Cancer): "After comparing hospitals in Seoul and Shanghai, this facility boasts the latest Gamma Knife equipment and delivers the most effective treatment. I'm now back working in Korea, undergoing regular video follow-ups, and everything is normal."

VIII. Contact Information & Transportation Guide

Hospital Address: No. 1200 Zhangheng Road, Pudong New Area, Shanghai (within Shanghai International Medical Park)

Telephone: 021-5080 6666 (Main Switchboard); 400-821-5888 (International Patient Hotline)

Transportation Routes:

• Subway: Take Line 2 to “Zhangjiang Hi-Tech Station” (Exit 2), transfer to Pudong Bus Route 1 to “Zhangheng Road-Keyuan Road Station”; or take Line 16 to “Luoshan Road Station” (Exit 2), then take a taxi for approximately 10 minutes.

• Bus: Pudong Line 1, Line 1090, Line 1099 to “Zhangheng Road-Keyuan Road Station”; Bridge Line 6, Pudong Line 25 to “Zhangjiang Metro Station”, then walk 10 minutes.

• Driving: The hospital features an underground parking garage (Fee: ¥5/hour, daily maximum ¥50). Navigate to “Shanghai Gamma Knife Hospital” for direct access.

Conclusion

Shanghai Gamma Knife Hospital centers its expertise around gamma knife technology and distinguishes itself through international-standard services. We continuously advance technological innovation and clinical translation in precision oncology treatment. Whether addressing complex critical conditions or serving international patients, the hospital remains steadfast in its commitment to “maximizing patient benefit,” striving to become a trusted guardian of health for cancer patients worldwide.

Document dated 2025-09-15 10:55 Modify